A liquid optical tip for single molecule imaging using gold nanoparticles

Y. Yang, D. P. Tsai, S. Xiong, A. Q. Liu

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

This paper reports liquid optical tip in a microchannel is controlled by the flow rates of three laminar flows. Unlike the solid optical tip, liquid optical tip provides good optical interfaces, which can be controlled dynamically. In the design of the optofluidic chip, the core and the cladding flow streams of the liquid waveguide is formed using calcium chloride (CaCl 2) and deionized water, respectively. The diffusion of CaCl 2 between the microfluidic laminar flows establishes a gradient refractive index distribution to form the optical tip. Based on the results, the optical intensity at the tip is increased by 15 times.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages914-916
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - Nov 2009
Externally publishedYes
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 1 Nov 20095 Nov 2009

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period1/11/095/11/09

Keywords

  • Nanoparticles
  • Optics
  • Optofluidic

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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