A highly selective FRET-based fluorescent probe for detection of cysteine and homocysteine

Hoi Yan Shiu; Hiu Chi Chong; Yun Chung Leung; Man Kin Wong; Chi Ming Che

doi:10.1002/chem.200903121

A highly selective FRET-based fluorescent probe for detection of cysteine and homocysteine

Hoi Yan Shiu, Hiu Chi Chong, Yun Chung Leung, Man Kin Wong, Chi Ming Che

Research output: Journal article publication › Journal article › Academic research › peer-review

112 Citations (Scopus)

Abstract

Fluorescent probe: A "turn-on" FRET-based fluorescent probe for selective detection of cysteine (Cys) and homocysteine (Hey) under physiological conditions was synthesised (see figure). The probe features excellent selectivity, fast response times and good linearity towards Cys and Hey detection KGaA.

Original language	English
Pages (from-to)	3308-3313
Number of pages	6
Journal	Chemistry - A European Journal
Volume	16
Issue number	11
DOIs	https://doi.org/10.1002/chem.200903121
Publication status	Published - 15 Mar 2010

Keywords

Bioimaging
Fluorescence
FRET
Quenchers
Thiols

ASJC Scopus subject areas

General Chemistry

More information

10.1002/chem.200903121

Cite this

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abstract = "Fluorescent probe: A {"}turn-on{"} FRET-based fluorescent probe for selective detection of cysteine (Cys) and homocysteine (Hey) under physiological conditions was synthesised (see figure). The probe features excellent selectivity, fast response times and good linearity towards Cys and Hey detection KGaA.",

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author = "Shiu, {Hoi Yan} and Chong, {Hiu Chi} and Leung, {Yun Chung} and Wong, {Man Kin} and Che, {Chi Ming}",

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AU - Shiu, Hoi Yan

AU - Chong, Hiu Chi

AU - Leung, Yun Chung

AU - Wong, Man Kin

AU - Che, Chi Ming

PY - 2010/3/15

Y1 - 2010/3/15

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AB - Fluorescent probe: A "turn-on" FRET-based fluorescent probe for selective detection of cysteine (Cys) and homocysteine (Hey) under physiological conditions was synthesised (see figure). The probe features excellent selectivity, fast response times and good linearity towards Cys and Hey detection KGaA.

KW - Bioimaging

KW - Fluorescence

KW - FRET

KW - Quenchers

KW - Thiols

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U2 - 10.1002/chem.200903121

DO - 10.1002/chem.200903121

M3 - Journal article

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SN - 0947-6539

VL - 16

SP - 3308

EP - 3313

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

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ER -

A highly selective FRET-based fluorescent probe for detection of cysteine and homocysteine

Abstract

Keywords

ASJC Scopus subject areas

More information

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