A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

On Ying Yuen; Shun Man Wong; Kin Fai Chan; Chau Ming So; Fuk Yee Kwong

doi:10.1055/s-0033-1338660

A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

On Ying Yuen, Shun Man Wong, Kin Fai Chan, Chau Ming So, Fuk Yee Kwong

Research output: Journal article publication › Journal article › Academic research › peer-review

11 Citations (Scopus)

Abstract

General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).

Original language	English
Article number	ss-2014-h0287-op
Pages (from-to)	2826-2832
Number of pages	7
Journal	Synthesis (Germany)
Volume	46
Issue number	20
DOIs	https://doi.org/10.1055/s-0033-1338660
Publication status	Published - 16 Oct 2014

Keywords

aryl chloride
arylation
palladium
potassium aryltrifluoroborates
Suzuki-Miyaura reaction
water

ASJC Scopus subject areas

Catalysis
Organic Chemistry

More information

10.1055/s-0033-1338660

Cite this

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title = "A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex",

abstract = "General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).",

keywords = "aryl chloride, arylation, palladium, potassium aryltrifluoroborates, Suzuki-Miyaura reaction, water",

author = "Yuen, {On Ying} and Wong, {Shun Man} and Chan, {Kin Fai} and So, {Chau Ming} and Kwong, {Fuk Yee}",

year = "2014",

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doi = "10.1055/s-0033-1338660",

language = "English",

volume = "46",

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journal = "Synthesis (Germany)",

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}

A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex. / Yuen, On Ying; Wong, Shun Man; Chan, Kin Fai et al.
In: Synthesis (Germany), Vol. 46, No. 20, ss-2014-h0287-op, 16.10.2014, p. 2826-2832.

Research output: Journal article publication › Journal article › Academic research › peer-review

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AU - Yuen, On Ying

AU - Wong, Shun Man

AU - Chan, Kin Fai

AU - So, Chau Ming

AU - Kwong, Fuk Yee

PY - 2014/10/16

Y1 - 2014/10/16

N2 - General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).

AB - General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).

KW - aryl chloride

KW - arylation

KW - palladium

KW - potassium aryltrifluoroborates

KW - Suzuki-Miyaura reaction

KW - water

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U2 - 10.1055/s-0033-1338660

DO - 10.1055/s-0033-1338660

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EP - 2832

JO - Synthesis (Germany)

JF - Synthesis (Germany)

IS - 20

M1 - ss-2014-h0287-op

ER -

A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

Abstract

Keywords

ASJC Scopus subject areas

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