A custom CMOS camera for sensitive SPR measurement

Roger A. Light; Richard J. Smith; Nicholas S. Johnston; Michael Geoffrey Somekh

doi:10.1109/FOI.2011.6154832

A custom CMOS camera for sensitive SPR measurement

Roger A. Light, Richard J. Smith, Nicholas S. Johnston, Michael Geoffrey Somekh

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

In surface plasmon imaging, a sample is placed on a glass prism that has been coated with a metal film, usually gold. When illuminated at the appropriate angle, plasmons are generated in the gold surface and there is both a sharp dip in the reflectivity of the gold and a strong phase shift in the reflected light. The plasmon angle is very sensitive to the conditions on the gold surface, which makes it potentially very useful in label-free biological measurements, where the amount of a particular protein in a sample can be determined by how much binds to antibodies printed on the gold surface and changes the local surface properties.

Original language	English
Title of host publication	2011 Functional Optical Imaging, FOI 2011
DOIs	https://doi.org/10.1109/FOI.2011.6154832
Publication status	Published - 1 Dec 2011
Externally published	Yes
Event	2011 Functional Optical Imaging, FOI 2011 - Ningbo, China Duration: 3 Dec 2011 → 4 Dec 2011

Conference

Conference	2011 Functional Optical Imaging, FOI 2011
Country/Territory	China
City	Ningbo
Period	3/12/11 → 4/12/11

ASJC Scopus subject areas

Computer Vision and Pattern Recognition

More information

10.1109/FOI.2011.6154832

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title = "A custom CMOS camera for sensitive SPR measurement",

abstract = "In surface plasmon imaging, a sample is placed on a glass prism that has been coated with a metal film, usually gold. When illuminated at the appropriate angle, plasmons are generated in the gold surface and there is both a sharp dip in the reflectivity of the gold and a strong phase shift in the reflected light. The plasmon angle is very sensitive to the conditions on the gold surface, which makes it potentially very useful in label-free biological measurements, where the amount of a particular protein in a sample can be determined by how much binds to antibodies printed on the gold surface and changes the local surface properties.",

author = "Light, {Roger A.} and Smith, {Richard J.} and Johnston, {Nicholas S.} and Somekh, {Michael Geoffrey}",

year = "2011",

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doi = "10.1109/FOI.2011.6154832",

language = "English",

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AU - Smith, Richard J.

AU - Johnston, Nicholas S.

AU - Somekh, Michael Geoffrey

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N2 - In surface plasmon imaging, a sample is placed on a glass prism that has been coated with a metal film, usually gold. When illuminated at the appropriate angle, plasmons are generated in the gold surface and there is both a sharp dip in the reflectivity of the gold and a strong phase shift in the reflected light. The plasmon angle is very sensitive to the conditions on the gold surface, which makes it potentially very useful in label-free biological measurements, where the amount of a particular protein in a sample can be determined by how much binds to antibodies printed on the gold surface and changes the local surface properties.

AB - In surface plasmon imaging, a sample is placed on a glass prism that has been coated with a metal film, usually gold. When illuminated at the appropriate angle, plasmons are generated in the gold surface and there is both a sharp dip in the reflectivity of the gold and a strong phase shift in the reflected light. The plasmon angle is very sensitive to the conditions on the gold surface, which makes it potentially very useful in label-free biological measurements, where the amount of a particular protein in a sample can be determined by how much binds to antibodies printed on the gold surface and changes the local surface properties.

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U2 - 10.1109/FOI.2011.6154832

DO - 10.1109/FOI.2011.6154832

M3 - Conference article published in proceeding or book

SN - 9781467304511

BT - 2011 Functional Optical Imaging, FOI 2011

T2 - 2011 Functional Optical Imaging, FOI 2011

Y2 - 3 December 2011 through 4 December 2011

ER -

A custom CMOS camera for sensitive SPR measurement

Abstract

Conference

ASJC Scopus subject areas

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