A custom CMOS camera for sensitive SPR measurement

Roger A. Light, Richard J. Smith, Nicholas S. Johnston, Michael Geoffrey Somekh

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

In surface plasmon imaging, a sample is placed on a glass prism that has been coated with a metal film, usually gold. When illuminated at the appropriate angle, plasmons are generated in the gold surface and there is both a sharp dip in the reflectivity of the gold and a strong phase shift in the reflected light. The plasmon angle is very sensitive to the conditions on the gold surface, which makes it potentially very useful in label-free biological measurements, where the amount of a particular protein in a sample can be determined by how much binds to antibodies printed on the gold surface and changes the local surface properties.
Original languageEnglish
Title of host publication2011 Functional Optical Imaging, FOI 2011
DOIs
Publication statusPublished - 1 Dec 2011
Externally publishedYes
Event2011 Functional Optical Imaging, FOI 2011 - Ningbo, China
Duration: 3 Dec 20114 Dec 2011

Conference

Conference2011 Functional Optical Imaging, FOI 2011
CountryChina
CityNingbo
Period3/12/114/12/11

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition

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