A convenient synthesis of anthranilic acids by Pd-catalyzed direct intermolecular ortho-C-H amidation of benzoic acids

Ka Ho Ng, Fo Ning Ng, Wing Yiu Yu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

61 Citations (Scopus)

Abstract

An efficient method for synthesis of anthranilic acids by Pd-catalyzed ortho-C-H amidation of benzoic acids is disclosed. The amidation is proposed to proceed by carboxylate-assisted ortho-C-H palladation to form an arylpalladium(ii) complex, followed by nitrene insertion to the Pd-C bond.
Original languageEnglish
Pages (from-to)11680-11682
Number of pages3
JournalChemical Communications
Volume48
Issue number95
DOIs
Publication statusPublished - 11 Dec 2012

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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