A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

Cong Li, Wing Tak Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

57 Citations (Scopus)


Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.
Original languageEnglish
Pages (from-to)3217-3220
Number of pages4
JournalTetrahedron Letters
Issue number17
Publication statusPublished - 22 Apr 2002
Externally publishedYes


  • Alkylation
  • Cyclam
  • Cyclen
  • Synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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