With the global population ageing rapidly, Alzheimer’s disease (AD) is particularly prominent in older adults, which has an insidious onset followed by gradual, irreversible deterioration in cognitive domains (memory, communication, etc). Thus the detection of Alzheimer’s disease is crucial for timely intervention to slow down disease progression. This paper presents a comparative study of different acoustic and linguistic features for the AD detection using various classifiers. Experimental results on ADReSS dataset reflect that the proposed models using ComParE, X-vector, Linguistics, TF-IDF and BERT features are able to detect AD with high accuracy and sensitivity, and are comparable with the state-of-the-art results reported. While most previous work used manual transcripts, our results also indicate that similar or even better performance could be obtained using automatically recognized transcripts over manually collected ones. This work achieves accuracy scores at 0.67 for acoustic features and 0.88 for linguistic features on either manual or ASR transcripts on the ADReSS Challenge1 test set.