Abstract
In this article, a class of transformed hazards models is proposed for recurrent gap time data, including both the proportional and additive hazards models as special cases. An estimating equation-based inference procedure is developed for the model parameters, and the asymptotic properties of the resulting estimators are established. In addition, a lack-of-fit test is presented to assess the adequacy of the model. The finite sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a clinic study on chronic granulomatous disease (CGD) is illustrated.
Original language | English |
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Pages (from-to) | 151-167 |
Number of pages | 17 |
Journal | Computational Statistics and Data Analysis |
Volume | 83 |
DOIs | |
Publication status | Published - 1 Jan 2015 |
Keywords
- Estimating equations
- Gap times
- Model checking
- Recurrent events
- Transformed hazards model
ASJC Scopus subject areas
- Statistics and Probability
- Computational Mathematics
- Computational Theory and Mathematics
- Applied Mathematics