Abstract
Dielectrophoresis (DEP) has widely been used for manipulation and patterning of biological cells. In this paper, a novel multi-layer scaffold structure was designed for patterning cells in 3D via dielectrophoresis. Honeycomb patterns were integrated in each layer of the structure in order to pattern cells into bone-like tissues. When a voltage was supplied to the scaffold structure, non-uniform electric fields were established to manipulate cells automatically, forming honeycomb-shaped patterns at different layers. To confirm the proposed cell manipulation mechanism, the electric fields were simulated and the structure was examined through experiments. Different voltage inputs were tested and a voltage input of 20V can form a uniform and complete hexagon patterns. The results show that this novel 3D scaffold is able to manipulate biological cells in 3D via dielectrophoresis rapidly.
Original language | English |
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Title of host publication | 2015 IEEE International Conference on Information and Automation, ICIA 2015 - In conjunction with 2015 IEEE International Conference on Automation and Logistics |
Publisher | IEEE |
Pages | 1680-1685 |
Number of pages | 6 |
ISBN (Electronic) | 9781467391047 |
DOIs | |
Publication status | Published - 28 Sept 2015 |
Externally published | Yes |
Event | 2015 IEEE International Conference on Information and Automation, ICIA 2015 - In conjunction with 2015 IEEE International Conference on Automation and Logistics - Yunnan, China Duration: 8 Aug 2015 → 10 Aug 2015 |
Conference
Conference | 2015 IEEE International Conference on Information and Automation, ICIA 2015 - In conjunction with 2015 IEEE International Conference on Automation and Logistics |
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Country/Territory | China |
City | Yunnan |
Period | 8/08/15 → 10/08/15 |
Keywords
- Bones
- Computer architecture
- Dielectrophoresis
- Electric fields
- Force
- Microprocessors
- Three-dimensional displays
ASJC Scopus subject areas
- Computer Networks and Communications
- Human-Computer Interaction
- Computational Theory and Mathematics
- Control and Systems Engineering
- Computer Vision and Pattern Recognition
- Computer Science Applications