2-[(1E,4E)-2-(4-Methoxy-phen-yl)-3H-benzo[b][1,4]diazepin-4-yl]phenol

Muhammad Zia-Ul-Haq; Mehwash Zia; Ghulam Qadeer; Nasim Hasan Rama; Wai Yeung Wong

doi:10.1107/S1600536807034630

2-[(1E,4E)-2-(4-Methoxy-phen-yl)-3H-benzo[b][1,4]diazepin-4-yl]phenol

Muhammad Zia-Ul-Haq, Mehwash Zia, Ghulam Qadeer, Nasim Hasan Rama, Wai Yeung Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

1 Citation (Scopus)

Abstract

The title compound, C22H18N2O2, is a biologically active 1,5-benzodiazepine derivative, containing three planar six-membered rings and one nonplanar seven-membered ring. The six-membered rings A (phenol), B (fused benzene) and C (methoxyphenyl) are oriented with respect to each other at dihedral angles of 39.22 (2) (A/B), 87.31 (3) (A/C) and 54.42 (3)° (B/C). The seven-membered ring adopts a near-boat conformation. In the crystal structure, intra-molecular O - H⋯N and inter-molecular C - H⋯O hydrogen bonds are present.

Original language	English
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	63
Issue number	8
DOIs	https://doi.org/10.1107/S1600536807034630
Publication status	Published - 31 Jul 2007
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

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10.1107/S1600536807034630

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title = "2-[(1E,4E)-2-(4-Methoxy-phen-yl)-3H-benzo[b][1,4]diazepin-4-yl]phenol",

abstract = "The title compound, C22H18N2O2, is a biologically active 1,5-benzodiazepine derivative, containing three planar six-membered rings and one nonplanar seven-membered ring. The six-membered rings A (phenol), B (fused benzene) and C (methoxyphenyl) are oriented with respect to each other at dihedral angles of 39.22 (2) (A/B), 87.31 (3) (A/C) and 54.42 (3)° (B/C). The seven-membered ring adopts a near-boat conformation. In the crystal structure, intra-molecular O - H⋯N and inter-molecular C - H⋯O hydrogen bonds are present.",

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T1 - 2-[(1E,4E)-2-(4-Methoxy-phen-yl)-3H-benzo[b][1,4]diazepin-4-yl]phenol

AU - Zia-Ul-Haq, Muhammad

AU - Zia, Mehwash

AU - Qadeer, Ghulam

AU - Rama, Nasim Hasan

AU - Wong, Wai Yeung

PY - 2007/7/31

Y1 - 2007/7/31

N2 - The title compound, C22H18N2O2, is a biologically active 1,5-benzodiazepine derivative, containing three planar six-membered rings and one nonplanar seven-membered ring. The six-membered rings A (phenol), B (fused benzene) and C (methoxyphenyl) are oriented with respect to each other at dihedral angles of 39.22 (2) (A/B), 87.31 (3) (A/C) and 54.42 (3)° (B/C). The seven-membered ring adopts a near-boat conformation. In the crystal structure, intra-molecular O - H⋯N and inter-molecular C - H⋯O hydrogen bonds are present.

AB - The title compound, C22H18N2O2, is a biologically active 1,5-benzodiazepine derivative, containing three planar six-membered rings and one nonplanar seven-membered ring. The six-membered rings A (phenol), B (fused benzene) and C (methoxyphenyl) are oriented with respect to each other at dihedral angles of 39.22 (2) (A/B), 87.31 (3) (A/C) and 54.42 (3)° (B/C). The seven-membered ring adopts a near-boat conformation. In the crystal structure, intra-molecular O - H⋯N and inter-molecular C - H⋯O hydrogen bonds are present.

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U2 - 10.1107/S1600536807034630

DO - 10.1107/S1600536807034630

M3 - Journal article

SN - 1600-5368

VL - 63

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 8

ER -

2-[(1E,4E)-2-(4-Methoxy-phen-yl)-3H-benzo[b][1,4]diazepin-4-yl]phenol

Abstract

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