Abstract
A series of P,O-type indolylphosphine ligands with different substituted variants have been synthesized by a simple one-pot protocol from readily available and inexpensive materials. These ligands show "substituent effect" with respected to the efficacy in promoting palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl chlorides. This new Pd/L1 catalyst system particularly allows the catalyst loading reaching the level of 0.01 mol% Pd.
Translated title of the contribution | Facile One-Pot Assembly of New 5-Substituted P,O-Type Indolylphosphine Ligands for Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling of Aryl Chlorides |
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Original language | Chinese (Simplified) |
Pages (from-to) | 3338-3346 |
Number of pages | 9 |
Journal | Chinese Journal of Organic Chemistry |
Volume | 40 |
Issue number | 10 |
DOIs | |
Publication status | Published - 1 Oct 2020 |
Keywords
- Cross-coupling
- Ligand design
- P,O-ligand
- Palladium
- Phosphine
ASJC Scopus subject areas
- Organic Chemistry