光流控光镊操控研究进展

Optical tweezers，which utilize optical forces from the momenta exchange of light and a parti⁃ cle，have advantages of being non-invasive and has a small manipulating size. Therefore，they have impor⁃ tant applications in the biomedical，physical，and chemical sciences. Optical tweezers at the early stage manipulate single or multiple particles in a motionless environment and can be classified into various classi⁃ cal categories，such as single/multiple-beam optical tweezers，holographic optical tweezers，plasmon opti⁃ cal tweezers，fiber optical tweezers，optical tweezers with special forces and torques，opto-thermal-electri⁃ cal tweezers，etc. Optical tweezers later fuse with the optofluidic technique，increasing manipulating quan⁃ tity and efficiency. This study reviews and comments on the recent progresses of optofluidic manipulation by focusing on the categories of optofluidic optical tweezers，mechanisms of optical tweezers as well as their biomedical applications. Meanwhile，potential challenges of optofluidic manipulation are summa⁃ rized. In addition，perspectives on the future developments of optofluidic optical tweezers such as high-throughput manipulation and detection of single viruses as well as light-driven microrobots are provided.