Yun Chung Leung

Professor, Department of Applied Biology and Chemical Technology

https://orcid.org/0000-0003-3590-7027

Phone34008661
Emailthomas.yun-chung.leung@polyu.edu.hk

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

Research activity per year

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Personal profile

Education/Academic qualification

Bachelor of Science in Chemistry and Biochemistry, University of London

Doctor of Philosophy in Molecular Biology, University of Oxford

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2543 Citations
27 h-Index
84 Journal article
73 Conference presentation (not published in journal/proceeding/book)
4 Chapter in an edited book (as author)

A bioengineered arginine-depleting enzyme as a long-lasting therapeutic agent against cancer
Chung, S. F., Kim, C. F., Tam, S. Y., Choi, M. C., So, P. K., Wong, K. Y., Leung, Y. C. & Lo, W. H., 1 May 2020, In: Applied Microbiology and Biotechnology. 104, 9, p. 3921-3934 14 p.
Research output: Journal article publication › Journal article › Academic research › peer-review

5 Citations (Scopus)
A modified arginine-depleting enzyme NEI-01 inhibits growth of pancreatic cancer cells
Chow, J. P. H., Cai, Y., Chow, D. T. L., Chung, S. H. K., Chau, K. C., Ng, K. Y., Leung, O. M., Wong, R. M. H., Law, A. W. L., Leung, Y. O., Kwok, S. Y. & Leung, Y. C., Apr 2020, In: PLoS ONE. 15, 4, e0231633.
Research output: Journal article publication › Journal article › Academic research › peer-review

Open Access

1 Citation (Scopus)
Arginine deprivation inhibits pancreatic cancer cell migration, invasion and EMT via the down regulation of Snail, Slug, Twist, and MMP1/9
Wang, H., Li, Q. F., Chow, H., Choi, S. & Leung, Y. C., 1 Feb 2020, In: Journal of Physiology and Biochemistry. 76, 1, p. 73-83 11 p.
Research output: Journal article publication › Journal article › Academic research › peer-review

4 Citations (Scopus)
Bioisosteric investigation of ebselen: Synthesis and in vitro characterization of 1,2-benzisothiazol-3(2H)-one derivatives as potent New Delhi metallo-β-lactamase inhibitors
Jin, W. B., Xu, C., Cheung, Q., Gao, W., Zeng, P., Liu, J., Chan, E. W. C., Leung, Y. C., Chan, T. H., Wong, K. Y., Chen, S. & Chan, K. F., Jul 2020, In: Bioorganic Chemistry. 100, 103873.
Research output: Journal article publication › Journal article › Academic research › peer-review

1 Citation (Scopus)
Mono-PEGylation of a Thermostable Arginine-Depleting Enzyme for the Treatment of Lung Cancer
Chung, S. F., Kim, C. F., Kwok, S. Y., Tam, S. Y., Chen, Y. W., Chong, H. C., Leung, S. L., So, P. K., Wong, K. Y., Leung, Y. C. & Lo, W. H., 2 Jun 2020, In: International Journal of Molecular Sciences. 21, 12, p. 1-17 17 p., 4234.
Research output: Journal article publication › Journal article › Academic research › peer-review

Open Access

3 Citations (Scopus)

2013 Higher Education Outstanding Scientific Research Output Awards - Natural Science Award (Second Class)
Wong, Kwok Yin (Recipient), Leung, Yun Chung (Recipient) & CHAN, P. H. (Recipient), Mar 2014
Prize: Prize (research)
2013 Higher Education Outstanding Scientific Research Output Awards – Natural Science Award (Second Class)
Wong, Kwok Yin (Recipient), Leung, Yun Chung (Recipient) & CHAN, P. H. (Recipient), Mar 2014
Prize: Prize (research)
Arginine depletion with pegylated recombinant human arginase as a novel method in the treatment of liver cancer
Leung, Yun Chung (Recipient), Lo, W. H. (Recipient) & CHENG, P. (Recipient), Apr 2005
Prize: Prize (research)
Arginine depletion with pegylated recombinant human arginase as a novel method in the treatment of liver cancer
Leung, Yun Chung (Recipient), Lo, W. H. (Recipient) & CHENG, P. (Recipient), Jan 2005
Prize: Prize (research)
Fast biosensor for detection of harmful substance in food
Wong, Kwok Yin (Recipient), Leung, Yun Chung (Recipient) & CHAN, P. (Recipient), Sep 2004
Prize: Prize (research)