Research output per year
Research output per year
Personal profile
Biography
Dr. Tan received the Bachelor degree in Mechanical Engineering from University of Science and Technology of China in 2005 and his PhD degree in Biomedical Engineering from both City University of Hong Kong and University of Science and Technology of China in 2010. He completed his postdoctoral fellowship in University of Illinois at Urbana-Champaign from 2011-2015. Since July 2015, Dr. Tan joined the Department of Biomedical Engineering at PolyU as Assistant Professor. Dr. Tan’s research interest includes cell mechanics and mechanobiology, especially the fundamental roles of mechanical forces in tumor metastasis. His research has been supported by many external grants, including 2 Hong Kong Research Grant Council General Research Fund (GRF), 1 Hong Kong Research Grant Council Collaborative Research Fund (CRF; Co-PI), 2 National Natural Science Foundation of China General Programme (NSFC), and 2 Shenzhen Science and Technology Innovation Commission Basic Research (STIC).
Research interests
Mechanobiology; Mechano-oncology; Tumour Metastasis; Cell Mechanics; Cancer Stem Cell.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, City University of Hong Kong
Bachelor of Engineering, University of Science and Technology of China
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Collaborations and top research areas from the last five years
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Research output
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Cell mechanics regulate the migration and invasion of hepatocellular carcinoma cells via JNK signaling
Wang, J., Zhang, B., Chen, X., Xin, Y., Li, K., Zhang, C., Tang, K. & Tan, Y., 1 Mar 2024, In: Acta Biomaterialia. 176, p. 321-333 13 p.Research output: Journal article publication › Journal article › Academic research › peer-review
6 Citations (Scopus) -
Circulating tumor cells with metastasis-initiating competence survive fluid shear stress during hematogenous dissemination through CXCR4-PI3K/AKT signaling
Xin, Y., Hu, B., Li, K., Hu, G., Zhang, C., Chen, X., Tang, K., Du, P. & Tan, Y., 28 May 2024, In: Cancer Letters. 590, 216870.Research output: Journal article publication › Journal article › Academic research › peer-review
3 Citations (Scopus) -
Neoteric Semiembedded β-Tricalcium Phosphate Promotes Osteogenic Differentiation of Mesenchymal Stem Cells under Cyclic Stretch
Dai, Y., Xie, Q., Zhang, Y., Sun, Y., Zhu, S., Wang, C., Tan, Y. & Gou, X., 21 Feb 2024, In: ACS Applied Materials and Interfaces. 16, 7, p. 8289-8300 12 p.Research output: Journal article publication › Journal article › Academic research › peer-review
Open Access5 Citations (Scopus) -
Adhesion to the Brain Endothelium Selects Breast Cancer Cells with Brain Metastasis Potential
Zhang, B., Li, X., Tang, K., Xin, Y., Hu, G., Zheng, Y., Li, K., Zhang, C. & Tan, Y., 11 Apr 2023, In: International Journal of Molecular Sciences. 24, 8, 7087.Research output: Journal article publication › Journal article › Academic research › peer-review
Open Access15 Citations (Scopus) -
Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine
Xin, Y., Li, K., Huang, M., Liang, C., Siemann, D., Wu, L., Tan, Y. & Tang, X., 20 Oct 2023, In: Oncogene. 42, 47, p. 3457-3490 34 p.Research output: Journal article publication › Review article › Academic research › peer-review
Open Access36 Citations (Scopus)
Prizes
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Best Paper Award in the 12th Chinese Biomechanics Conference
Tan, Y. (Recipient), 20 Aug 2018
Prize: Prize (research)
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Best Paper Award in the 6th International Conference on Biomedical Engineering and Biotechnology
Tan, Y. (Recipient), 20 Oct 2017
Prize: Prize (research)
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Activities
- 2 Editorial work for journals
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Biology (Journal)
Tan, Y. (Guest editor)
25 Feb 2020Activity: Publication peer-review and editorial work › Editorial work for journals
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PLoS ONE (Journal)
Tan, Y. (Editorial board member)
Jun 2019Activity: Publication peer-review and editorial work › Editorial work for journals
Press/Media
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Manipulation of the Nanoscale Presentation of Integrin Ligand Produces Cancer Cells with Enhanced Stemness and Robust Tumorigenicity
Wong, S. H. & Tan, Y.
4/12/21
1 item of Media coverage
Press/Media