Personal profile
Biography
Prof. Dennis Yan-yin Tse obtained his BSc Optometry and PhD degrees from The Hong Kong Polytechnic University (PolyU). His early research focused on the modulation of refractive development by optical defocus in animal models. The basic scientific discoveries were later translated into clinical applications in the form of contact lenses and eyeglasses that effectively control myopia progression in children. Upon receiving his PhD, he spent two years in Australia as a postdoctoral fellow as part of a collaborative myopia research project between PolyU and the University of Newcastle. In 2011, he joined the Dept. of Ophthalmology of Baylor College of Medicine in the United States, where he received further postdoctoral training on retinal neuroscience from Prof. Samuel Miao-Sin Wu. He returned to his alma mater in late 2014 and is currently an Associate Professor in the School of Optometry. He is currently responsible for teaching the subject of “Management and Prevention of Refractive Error” and topics of colour vision in the School of Optometry.
Prof. Tse’s current research interests include mechanism and treatment of myopia, ophthalmic lens design, head-mount display technology, retinal neuroscience and the role of autophagy and oxidation in retinal degenerations. Prof. Tse was named the 2012 Loris and David Rich Scholar by the International Retinal Research Foundation for his research on the pathogenesis of glaucoma. He was awarded a Grand Prize and Gold Medal with Jury's Commendation at the 39th International Exhibition of Inventions of Geneva in 2011, and a Faculty Award in Research and Scholarly Activities (Team) in 2020 for his research on myopia. His research team was also awarded the PolyU President’s Award for Outstanding Achievement 2021 (Knowledge Transfer). He was also an awardee of the Endeavour Cheung Kong Research Fellowship, and the Sir Edward Youde Memorial Fellowships in his earlier career. His research has been supported by the Research Impact Fund and General Research Fund from the Research Grants Council of HK, Innovation and Technology Support Programme, and Health@InnoHK cluster from the Innovation and Technology Commission of HK.
Research interests
- Retinal neuroscience
- Mechanism and treatment of myopia
- Role of autophagy and oxidation in retinal degenerations
Teaching
- Vision Science 4
- CMCM
- Visual Neuroscience
Education/Academic qualification
Doctor of Philosophy, The Hong Kong Polytechnic University
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Collaborations and top research areas from the last five years
Research output
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Defocus Coding and Transcriptomic Remodeling in the Mouse Myopic Retina
So, C. H., Zhang, T., Yang, K., Wang, J., Tse, Y. Y. & Pan, F. (Corresponding Author), May 2026, In: American Journal of Physiology - Cell Physiology. 330, 5, p. C1309-C1324 40 p., C-00011-2026.Research output: Journal article publication › Journal article › Academic research › peer-review
Open Access -
Microstructured Spectacle Lenses for Myopia Control
Tse, Y. Y., 3 Feb 2026.Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review
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Myopia Control Efficacy of Defocus Incorporated Multiple Segments Triple Enhanced Design Spectacle Lenses
Tse, Y. Y., Hon, Y., Chun, K. M., To, C. H., Leung, T. W. & Lam, C. S. Y., 5 Feb 2026, (Not published / presented only).Research output: Unpublished conference presentation (presented paper, abstract, poster) › Poster › Academic research › peer-review
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Six-Month Interim Analyses of the Efficacy of Defocus Incorporated Multiple Segments Triple Enhanced Design Spectacle Lenses for Myopia Control
Tse, Y. Y., 6 Feb 2026, (Not published / presented only).Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review
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Combination effect of optical defocus and low dose atropine in myopia control: Baseline demographics
Chun, K. M., Wan, S. H., Law, T. K., To, C. H. & Tse, Y. Y., 7 Jun 2025, (Not published / presented only).Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review
Prizes
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50th Geneva International Exhibition of Inventions 2025 - Gold Medal
Cheung, C. F. (Recipient), Wang, B. (Recipient), Ho, L. T. (Recipient), Zhong, W. (Recipient), Tse, Y. Y. (Recipient), Li, Z. (Recipient) & Gao, S. (Recipient), 9 Apr 2025
Prize: Prize (research)
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Asia International Innovation Invention Award (Gold Award)
Cheung, C. F. (Recipient), To, C. H. (Recipient), Leung, T. M. (Recipient), Wang, B. (Recipient), Tse, Y. Y. (Recipient), Lam, C. S. Y. (Recipient), Ho, L. T. (Recipient), Wong, C. M. (Recipient) & Wong, C. H. (Recipient), 23 Jun 2023
Prize: Prize (research)
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eLearning and Blended Learning Development Fund 2018/19
Ting, W. K. (Recipient), Pan, F. (Recipient), Chan, H. L. H. (Recipient), Cheong, M. Y. (Recipient), Neuville, J. M. (Recipient), Do, C. W. (Recipient), Tse, Y. Y. (Recipient), Ng, H. Y. L. (Recipient) & Eng, H. (Recipient), Sept 2018
Prize: Prize (teaching & learning)
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Faculty Award for Outstanding Achievement in Knowledge Transfer 2021
To, C. H. (Recipient), Lam, C. S. Y. (Recipient) & Tse, Y. Y. (Recipient), 1 Sept 2021
Prize: Prize (research)
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Registration Committee, The Optometrists Board (External organisation)
Tse, Y. Y. (Member)
Dec 2017 → …Activity: Office holder / membership of professional bodies › Office holder / member of board
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Scientific Reports (Journal)
Tse, Y. Y. (Editorial board member)
Sept 2016 → …Activity: Publication peer-review and editorial work › Editorial work for journals
Press/Media
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理大十科研獲批6500萬 研檢脊椎側彎及減慢近視
Tse, Y. Y., To, C. H. & Lam, C. S. Y.
14/02/19
1 item of Media coverage
Press/Media
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Simple sugar delays neurodegeneration caused by enzyme deficiency
20/06/18 → 21/06/18
4 items of Media coverage
Press/Media
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Sugar delays neurodegeneration caused by enzyme deficiency
20/06/18
2 items of Media coverage
Press/Media
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Research reveals strategy to potentially treat juvenile Batten disease 8 Feb 20171
8/02/17
1 item of Media coverage
Press/Media