20232023

Research activity per year

Personal profile

Biography

Biography

Dr. Jennifer Jingfang Bian obtained a first-class honor degree in Clinical Medicine from the school of Optometry and ophthalmology of Tianjin Medical University in 2009. From 2009 to 2012, she worked at Tianjin Medical University Eye Hospital and gained some experience in Optometry and ophthalmology. She later received a scholarship from PolyU for pursuing postgraduate study and obtained her PhD degree at the School of Optometry (SO) in 2021. Her PhD thesis mainly focused on Proteomics in lens-induced myopic (LIM) mammalian model. Apart from her PhD study, she actively participated in various research projects associated with myopia, glaucoma, and tear biomarkers. She also actively joined international conferences and obtained three conference awards. She also actively serves as a member of The Hong Kong Society of Mass Spectrometry, and the Ophthalmic testing group of the Ophthalmology Professional Committee of the China Medical Equipment Association. Dr. Bian was a Postdoctoral Fellow under Research Centre for SHARP Vision, PolyU Academy for Interdisciplinary Research (PAIR) before joining PolyU’s School of Optometry in 2023 as a Research Assistant Professor.

 

Research Overview

Dr. Bian’s main research interest is understanding myopia mechanism and pharmacological intervention using interdisciplinary approach. In her PhD study, she first developed and applied integrated next-generation proteomics to discover potential retinal biomarkers and related biochemical pathways in emmetropization and LIM guinea pigs. Over the same period, she also integrated proteomic and transcriptomic high-throughput approaches to provide multi-faceted insights into the interrelation of omics’ layers in myopia.  Her new research directions are to develop retinal cell-specific proteomics, single-cell transcriptomics, and Artificial intelligence (AI)-based analysis of multi-omics data approach. Dr. Bian is also interested in Traditional Chinese medicine (TCM) for myopia control and intraocular fluid biomarkers in ocular diseases.

Research Interests 

  • Myopia mechanism and intervention.
  • Traditional Chinese medicine (TCM) for myopia control
  • Retinal cell-specific proteomics.
  • Single-cell transcriptomics.
  • Artificial intelligence (AI) based multi-omics bioinformatics.
  • Intraocular fluid biomarkers in ocular diseases.

Education/Academic qualification

Doctor of Philosophy, The Hong Kong Polytechnic University

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  • Best Oral Presentation

    Cheung, Ka Wai (Recipient), Sze, Ying Hon (Recipient), Bian, Jingfang (Recipient), Li, King Kit (Recipient), Zhou, Lei (Recipient), To, Chi Ho (Recipient) & Lam, Chuen (Recipient), 12 Aug 2022

    Prize: Prize (research)