Research output per year
Research output per year
Personal profile
Biography
I received a Bachelor of Science in Optometry from The Hong Kong Polytechnic University (PolyU). After completing my PhD study at the same institution, I worked as a postdoctoral fellow and then a research associate at the University of Pennsylvania School of Medicine in the United States. After that, I returned to my alma mater as assistant professor and I am currently an associate professor in the School of Optometry, PolyU.
My research interest lies in the areas of aqueous humor dynamics and glaucoma pathophysiology. My research has been focused on cellular mechanisms responsible for modulating the rate of aqueous humor secretion, outflow facility and intraocular pressure (IOP). I have adopted an integrated approach using both in vitro and in vivo animal models to investigate the regulation of aqueous humor dynamics and its relationship to IOP. My goal is to unravel the mechanisms and signaling cascades underlying the regulation of ion transport and fluid dynamics in the mammalian eyes. Recently, we have also looked into the potential therapeutic functions of Traditional Chinese Medicine (TCM) in eye disease management.
Research interests
- Mechanism and regulation of aqueous humor dynamics and intraocular pressure (IOP)
- Pathophysiology of glaucoma
- Traditional Chinese Medicine for managing eye diseases
- Advanced technology for vision assessment
Teaching
- Visual Science
- Service-learning Subjects
- Optometry Clinical Placement
- Final Year Project
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bachelor of Science in Optometry, The Hong Kong Polytechnic University
Doctor of Philosophy, The Hong Kong Polytechnic University
External positions
Visiting Professor, Chengdu University of Traditional Chinese Medicine
2019 → 2024
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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A combinatorial approach based on Pluronic-127 containing flavonoid loaded solid lipid nanoparticles as localized platform for combating dry eye disease
Khan, S., Do, C. W., Ho, E. & Wong, K., 23 May 2024, (Not published / presented only).Research output: Unpublished conference presentation (presented paper, abstract, poster) › Poster › Academic research › peer-review
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A digoxin derivative that potently reduces intraocular pressure: efficacy and mechanism of action in different animal models
Barathi, V. A., Katz, A., Chaudhary, S. K., Li, H. L., Tai, D. M., Marcovich, A., Do, C. W. & Karlish, S. J. D. (Corresponding Author), May 2024, In: American Journal of Physiology - Cell Physiology. 326, 5, p. 1505-1519 15 p.Research output: Journal article publication › Journal article › Academic research › peer-review
Open Access -
Advancing Community-based Myopia Detection Through Smartphone Technology
Kiu, L. Y., Kwok, O. L., Leung, H. C., Tang, W. C., Cheung, M., Lee, P. H., Leong, H. V., Ngai, G., Chan, L. Y. L. & Do, C. W., 23 May 2024, (Not published / presented only).Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review
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BAICALEIN ANALOGS FOR USE IN NEUROPROTECTION AND REGULATION OF IMMUNE REACTIVITY
Do, C. W. (Inventor), To, C. H. (Inventor), PAN, L. (Inventor), CHEN Dongfeng (Inventor) & Cho, K.-S. (Inventor), 2024, Patent No. 11,826,341, 9 Feb 2022Research output: Patents, agreements, assignments and companies › Patents granted
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Biomimetic Nano-platform for the Treatment of Retinal Diseases
Li, H., Ho, E., Wong, K. & Do, C. W., 23 May 2024, (Not published / presented only).Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review
Prizes
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2nd Prize ""Cooperative learning through providing eye care and vision health service to the community" at International Contest on Blended Teaching & Learning (ICBTL2021)
Do, C. W. (Recipient), Chan, H. L. H. (Recipient), Chu, C. H. G. (Recipient), Chan, Y. Y. (Recipient), Lo, W. Y. (Recipient) & Chan, L. Y. L. (Recipient), 31 Dec 2021
Prize: Prize (teaching & learning)
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49th International Exhibition of Inventions Geneva - Gold medal
Tang, Y. M. (Recipient), Chan, H. S. (Recipient), Do, C. W. (Recipient), To, S. (Recipient), Hung , W. W. (Recipient), Ng, K. C. (Recipient), Li, D. (Recipient) & Kwok, C. P. (Recipient), 19 Apr 2024
Prize: Prize (research)
File -
CXO’s Editor Choice
Cui, Y. (Recipient), Pan, L. (Recipient), Lam, T. T. (Recipient), Wen, C. Y. (Recipient) & Do, C. W. (Recipient), May 2022
Prize: Prize (research)
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eLearning and Blended Learning Development Fund 2018/19
Ting, W. K. (Recipient), Pan, F. (Recipient), Chan, H. L. H. (Recipient), Cheong, M. Y. (Recipient), Neuville, J. M. (Recipient), Do, C. W. (Recipient), Tse, Y. Y. (Recipient), Ng, H. Y. L. (Recipient) & Eng, H. (Recipient), Sept 2018
Prize: Prize (teaching & learning)
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Emerging Trends & Hot topics
Li, H. L. (Recipient), Navarro, I. D. (Recipient), Ashpole, N. E. (Recipient), Lam, C. (Recipient), Chan, H. L. H. (Recipient), To, C. H. (Recipient), Stamer, W. D. (Recipient) & Do, C. W. (Recipient), 2015
Prize: Prize (research)
Activities
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Member of the Clinical Research Ethics Panel
Do, C. W. (Participant)
1 Nov 2022 → 30 Oct 2024Activity: Other activity types › Other
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Effects of baicalein on aqueous humor dynamics
Do, C. W. (Invited speaker)
Jan 2020Activity: Talk or presentation › Invited talk
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Experimental Eye Research (Journal)
Do, C. W. (Reviewer)
2019 → …Activity: Publication peer-review and editorial work › Editorial work for journals
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Drug News & Perspectives (Journal)
Do, C. W. (Reviewer)
2019 → …Activity: Publication peer-review and editorial work › Editorial work for journals
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Clinical and Experimental Optometry (Journal)
Do, C. W. (Reviewer)
2019 → …Activity: Publication peer-review and editorial work › Editorial work for journals